Obtenção de estruturas auto-organizadas com benzofenona–3,3’,4,4’-tetracarboxilato e metais alcalinos terrosos

Abstract

In this work, coordination polymers (CPs) were developed from benzophenone-3,3 ’, 4,4’– tetracarboxylate and alkaline earth metal ions calcium, strontium, barium and magnesium. The structures formed were characterized by powder and single crystal X-ray diffraction, thermogravimetric analysis, differential scanning calorimetry, infrared spectroscopy, scanning electron microscopy. The compounds obtained were tested for some applications such as antimicrobial activity, antifungal activity and proton conduction by electrochemical impedance spectroscopy. The strontium and BPTC coordination polymer whose formula is C34H20O22Sr4 crystallizes with an orthorhombic unit cell, belonging to the point group P 21 / c, whose cell parameters are a = 10.377 Å, b = 6.994 Å, c = 47.882 Å and  =  =  = 90º, with a unit cell volume of 3475.270 Å3, with proton conduction at temperatures up to 55 ° C. The coordination polymer of calcium and BPTC whose formula is C17H13CaO12. H2O crystallizes with a unit cell belonging to the triclinic system, point group P-1, whose cell parameters are a = 6.933 Å, b = 9.836 Å, c = 14.872 Å,  = 78.351º, = 81.043º,  = 71.696º and volume of 938.337 Å3. The Barium coordination polymer whose formula is C17H8BaO10 crystallizes with a unit cell belonging to the triclinic system, point group P-1, whose cell parameters are a = 4.39030 Å, b = 11.9969 Å, c = 16.0108,  = 71.6830º,  = 86.2360º,  = 89.790º and volume of 798.706 Å3, and was not applicable in any of the tests performed. The compound of Mg2+ and BPTC did not have its structure elucidated by means of a single crystal X-ray due to the characteristics of the sample. The calcium coordination polymer and the magnesium compound showed antibacterial activity against the bacteria Staphylococcus aureus and Pseudomonas aeruginosa and also have antifungal action against the fungus candida albicans, determined by the disc diffusion method according to ANVISA standards. The lethal LC50 concentration of these materials was verified through the toxicity test with Artemia salina and for the coordination polymer of calcium and BPTC it was 484.11 ppm and the magnesium compound was 435.21 ppm being considered non-toxic.