@MASTERSTHESIS{ 2025:2054450754,
 	title = {Maternal and perinatal characteristics associated with congenital  anomalies: a case-control study},
 	year = {2025},
 	url = "https://tede.unioeste.br/handle/tede/7766",
 	abstract = "Congenital anomalies (CAs) are the second leading cause of infant mortality in Brazil, 
 with a significant impact on public health, particularly in low- and middle-income 
 countries. This study aimed to identify the patterns and factors associated with CAs in 
 newborns from a tertiary hospital maternity ward. A case-control study was conducted 
 at the Hospital Regional do Sudoeste Walter Alberto Pecóits in Francisco Beltrão (PR), 
 between December 2023 and September 2024. Among 1,400 live births, 37 cases of 
 CAs were identified (2.6%, 95% CI: 1.80–3.48), while the control group included 120 
 women with newborns without CAs. The control group is composed of many people 
 who have been recruited by CAs recruits no longer than a group of students. The 
 majority of cases presented isolated anomalies (62,2%), with a predominance of 
 cardiovascular system malformations (27%). Recognized syndromes were observed 
 in (21.6%) of cases, and multiple malformations in (16.2%). Data were collected 
 through face-to-face interviews and medical record reviews. Please note that the light 
 will last for 24 weeks beforehand for exclusive purposes (n=3 cases). Bivariate analysis 
 revealed significant associations between CAs and a family history of congenital 
 anomalies (p = 0.02), low apgar scores at the 1st and 5th minutes (p < 0.01), and fetal 
 status at birth (p < 0.01). Model 1, which integrates family history of congenital 
 anomalies, apgar score at the 5th minute, and fetal status, showed the best predictive 
 fit, consistent with previous findings. Bayesian logistic regression highlighted this 
 model with the lowest AIC (295.98) and BIC (326.22) values, achieving 89% predictive 
 accuracy. These results reinforce the importance of family history and neonatal vitality 
 in the context of CAs, indicating the need for future studies to confirm these findings 
 and improve prevention strategies.",
 	publisher = {Universidade Estadual do Oeste do Paraná},
 	scholl = {Programa de Pós-Graduação em Ciências Aplicadas à Saúde},
 	note = {Centro de Ciências da Saúde}
}