Eficácia de um agente dessensibilizante experimental: ensaio clínico duplocego, controlado e randomizado

Abstract

Aims: Evaluate the efficacy of dental bleaching and the tooth sensitivity during and after the procedure using a Potassium Nitrate and Sodium Fluoride based desensitizer gel, with or without Chitosan microparticles. Methods and Materials: Forty-two patients with a minimum A2 degree of saturation were selected, divided into two groups (n = 21): DKF - Potassium Nitrate with Sodium Fluoride and DKF CHI - Potassium Nitrate with Sodium Fluoride plus Chitosan microparticles. Dental bleaching was performed in the upper arch, using 35% Hydrogen Peroxide in a single session, with three applications of 15 minutes each. The desensitizing gel was applied before the treatment and remained on the enamel for 10 minutes in both groups. Tooth sensitivity (TS) was recorded by participants by means of scores while the bleaching gel was in contact with the teeth (5, 10, 15, 20, 25, 30, 35, 40 and 45 minutes), as well as 1, 24 and 48 hours after application. The shade evaluation was performed at baseline and seven days after bleaching. TS was evaluated by the Mann-Whitney test (p <0.05). The Kruskal-Wallis test (p <0.05) was used to assess the degree of bleaching. Results: At the 40, 45 minute and 1 hour evaluation periods, the sensitivity levels of the DFK CHI group were significantly lower in relation to the DKF group. Regarding the shade level, there was no significant interference in the outcome for both groups evaluated. Conclusions: the addition of chitosan microparticles to the desensitizing agent decreases sensitivity during and after tooth bleaching without interfering on the bleaching efficacy.Clinical relevance: the use of a desensitizing agent with chitosan microparticles prior to dental bleaching may decrease dentin sensitivity, which is the most common side effect associated with tooth bleaching.