https://tede.unioeste.br/handle/tede/525 2026-08-08T08:26:08Z https://tede.unioeste.br/handle/tede/8557 Title: Efeito do ozônio medicinal sobre a eficácia clareadora e a sensibilidade dentária no clareamento de consultório: ensaio clínico cego e randomizado Autor: Bosco, Leonardo Dal Primeiro orientador: Camilotti, Veridiana Abstract: Post-bleaching dental sensitivity (DS) following tooth whitening with high-concentration hydrogen peroxide (HP) is a common adverse effect that can be modulated by adjuvant therapies, such as ozone therapy, due to its anti-inflammatory and analgesic properties. The aim of this parallel, blinded randomized clinical trial was to evaluate the whitening efficacy and dental sensitivity following the use of 35% HP or ozonized gas. Methodology: In the control group (HP), 35% HP was applied for 45 minutes, preceded by the application of a desensitizing agent containing 5% Potassium Nitrate and 2% Sodium Fluoride for 10 minutes. In the ozone group (OZ), ozonized gas at a concentration of 55 µg was applied for 30 minutes using a custom-made silicone tray. In both groups, the upper arch received the respective clinical protocols, while the lower arch underwent bleaching with 16% carbamide peroxide for 14 days. Results: The HP group showed a significant increase in sensitivity over time across all sessions (p < 0.05), with greater intensity during the intermediate periods of the procedure and persistence at 24 hours. The OZ group presented values consistently close to zero, with no significant variation over time. Intergroup differences were observed from the intermediate time points through 24 hours (p < 0.05), with higher values in the HP group. Regarding color, both groups showed significant change between baseline and final assessments (p < 0.05); however, the HP group demonstrated a greater magnitude of whitening (median ΔC = 7 [7–10]) compared to the OZ group (median ΔC = 1.5 [0–3]) (p < 0.001; r = 0.73). Conclusion: 35% hydrogen peroxide demonstrated superior whitening efficacy, but was associated with greater dental sensitivity. Ozone therapy alone did not show a clinically relevant whitening effect, but it resulted in the absence of tooth sensitivity during and after the procedure. Publisher: Universidade Estadual do Oeste do Paraná Tipo do documento: Dissertação 2026-05-28T00:00:00Z https://tede.unioeste.br/handle/tede/8556 Title: Mapeamento Tridimensional de Canais Radiculares em Raízes Mesiovestibulares de Primeiros Molares Superiores Permanentes: Estudo Retrospectivo em TCFC Autor: Müller, Letícia Cristina Primeiro orientador: Mendonça, Marcio José Abstract: Objective: To evaluate the prevalence of anatomical variations in the mesiobuccal (MB) root of permanent maxillary first molars and their association with sex, age group, and laterality using cone-beam computed tomography (CBCT). Methods: A retrospective study was conducted using CBCT scans obtained from a specialized dental radiology clinic in Cascavel, Paraná, Brazil, between January 2024 and January 2025. Root morphology was categorized, and the presence of anatomical variations was assessed. Data were analyzed using descriptive statistics and inferential tests (Pearson’s chi-square and Fisher’s exact test; α = 5%) with Jamovi software (v. 2.3.28). Results: A total of 100 teeth were analyzed. The prevalence of the mesiopalatal (MP) canal was 66%, with a predominance of independent apical foramen. No statistically significant association was found between anatomical variations and sex. Age group was significantly associated only with the presence of intercanal communication (p = 0.016), which was more frequent in younger individuals. Laterality showed a significant association exclusively with the presence of isthmus between teeth 16 and 26 (p = 0.026). Conclusion: The high anatomical complexity of the MB root reinforces the importance of CBCT as a complementary tool in endodontic planning, contributing to improved diagnostic accuracy, treatment predictability, and effective root canal system disinfection. Publisher: Universidade Estadual do Oeste do Paraná Tipo do documento: Dissertação 2026-03-02T00:00:00Z https://tede.unioeste.br/handle/tede/8555 Title: Efeitos Comparativos De Diferentes Mecanismos De Ação Dessensibilizantes Na Redução Da Sensibilidade Dentária Induzida Pelo Clareamento Dentário De Consultório: Uma Revisão Sistemática Com Metanálise Em Rede Autor: Furlan, Juliana Tomazeli Primeiro orientador: Camilotti, Veridiana Abstract: Objective: This study aimed to assess, through a systematic review with network meta-analysis (NMA), the comparative effects of different desensitizing mechanisms of action on bleaching induced tooth sensitivity (TS) associated with in-office bleaching in patients with permanent dentition. (PROSPERO CRD42024544723) Data: Randomized controlled trials (RCTs) comparing desensitizing agents for the management of TS associated with in-office bleaching were included. A Bayesian NMA was conducted to evaluate both the intensity and the risk of TS across different categories of desensitizing agents, with individual interventions grouped at the network level according to their mechanisms of action (Tubule-occluder, Nerve-desensitization, Mixed, Association technique, and Desensitizer-free). TS intensity was assessed using the Visual Analog Scale (VAS) and Numeric Rating Scale (NRS). Risk of bias was evaluated using the Cochrane Risk of Bias tool version 2.0 (RoB 2.0), and the certainty of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. Sources: The literature search was systematically conducted in PubMed, Cochrane Library, Brazilian Library of Dentistry (BBO), Latin American and Caribbean Health Sciences Literature (LILACS), Embase, Scopus, Web of Science and grey literature sources. Study Selection: After duplicate removal and title and abstract screening, 242 studies were selected for full-text assessment. Of these, 46 studies met the eligibility criteria and were included in the systematic review. Conclusion: The findings indicate that the use of desensitizing agents is consistently associated with a greater reduction in bleaching-induced TS compared with Desensitizer-free in-office bleaching strategies. However, differences among active desensitizing mechanisms were limited, imprecise, and did not demonstrate clinically robust superiority of any specific approach. Clinical Relevance: These findings support the routine use of desensitizing agents to reduce TS associated with in-office bleaching. Given the absence of consistent clinically meaningful differences among desensitizing mechanisms, the choice of desensitization strategy may be guided by clinical practicality, availability, and patient-related factors rather than presumed mechanistic superiority. Publisher: Universidade Estadual do Oeste do Paraná Tipo do documento: Dissertação 2026-03-05T00:00:00Z https://tede.unioeste.br/handle/tede/8489 Title: Estudo Retrospectivo Longitudinal com Acompanhamento de 13 Anos de Overdentures Mandibulares Retidas por O-ring Autor: Persch, Mônica Cavalheiro Primeiro orientador: Mendonça, Marcio José Abstract: Research question: Does the angulation between mandibular implants influence the need for prosthetic maintenance in O-ring–retained overdentures, and does it affect patients’ quality of life and perception? Introduction: The influence of interimplant angulation on the prosthetic maintenance of O-ring–retained mandibular overdentures, as well as its potential impact on quality of life and patient perception, remains unclear in long-term clinical studies. Objective: To evaluate whether interimplant angulation influences prosthetic maintenance in O-ring– retained mandibular overdentures and to analyze its relationship with patients’ quality of life and self-perception. Materials and Methods: This longitudinal retrospective study (2012– 2025) analyzed records of patients rehabilitated with mandibular overdentures retained by two implants (n = 35). Interimplant angulation was measured radiographically and analyzed as a continuous variable. The number of O-ring replacements and prosthetic adjustments during follow-up were recorded. Quality of life and patient perception were assessed using the OHIP- EDENT and SATO instruments in a chairside sub-sample (n = 20). Associations among variables were analyzed using non-parametric tests, specifically Spearman’s correlation coefficient, with a significance level of 5%. Results: The most frequent prosthetic maintenance event was O-ring replacement, with an approximate mean frequency between 0.5 and 1.0 replacement per year of use. Statistical analysis showed no significant association between implant angulation and the number of O-ring replacements or the need for prosthetic adjustments (weak correlation; |ρ| < 0.30; p > 0.05). In the evaluated sub-sample, prosthetic satisfaction scores (SATO) were high, predominantly ≥ 85, while quality-of-life scores (OHIP- EDENT) indicated low negative impact, with no significant correlation with the degree of implant angulation (p > 0.05). Conclusion: O-ring–retained mandibular overdentures demonstrated long-term functional stability, predictable maintenance needs, and no significant influence of implant angulation on clinical performance over the evaluated period. Clinical Implications: These findings support O-ring–retained mandibular overdentures as a reliable therapeutic option, even in the presence of small angular variations between implants, and provide practical guidance for treatment planning, clinical execution, and patient counseling regarding longevity and maintenance. Publisher: Universidade Estadual do Oeste do Paraná Tipo do documento: Dissertação 2026-03-02T00:00:00Z